The plot involves an alien race known as the Vortaak invading the Earth and assuming control of the planet's giant monsters, sending them to attack cities across the globe. Extra features include choice of several locations, and a 'destruction' mode (in which players compete to destroy buildings in a city) and 'melee' mode (in which up to four players can compete simultaneously). Extras include powerup orbs, which provide additional health, energy, unlock a finishing move, or summon Mothra for an airstrike. Army forces (missile and freeze tanks) and the monster Hedorah (which slows a monster's energy regeneration) are also present and sporadically attack all monsters. Each monster can use their signature beam attack and throw environmental objects. The player must defeat their opponents via punches, kicks, and limb attacks (usually a tail-attack).
The player plays as one of several giant monsters (eleven playable characters: Anguirus, Destoroyah, Gigan, Godzilla 90s, Godzilla 2000, King Ghidorah, Mecha-King Ghidorah, Megalon, Orga, Rodan, and Mechagodzilla). A similar but different game was later released for Game Boy Advance as Godzilla: Domination! A version for the Xbox with additional content was released in 2003. Godzilla: Destroy All Monsters Melee is a fighting game developed by Pipeworks Software and published by Infogrames under the Atari brand for GameCube in 2002.
